Botox vs Dysport vs Xeomin vs Jeuveau vs Letybo: Complete Comparison Guide

Choosing the right neurotoxin treatment can feel overwhelming when you’re facing options like Botox, Dysport, Xeomin, Jeuveau, and Letybo. At Elan Med Spa in Fayetteville, we offer the five most popular options, and as a physician-owned practice, we’re here to help you understand the differences so you can make an informed decision.

What They Have in Common

All five products are botulinum toxin type A injections that temporarily relax facial muscles to smooth wrinkles and prevent new lines from forming. They’re FDA-approved, safe when administered by trained professionals, and have been used millions of times with excellent safety profiles. Each works by blocking nerve signals to muscles, creating smoother, more youthful-looking skin.

The Key Differences

Botox is the original and most well-known option. It’s been on the market since 2002 and has the most extensive research backing. Results typically appear within 3-5 days and last 3-4 months. Botox is often considered the gold standard, with predictable results and widespread physician familiarity. It’s FDA-approved for cosmetic use as well as medical conditions like chronic migraines and excessive sweating.

Dysport spreads slightly more than Botox, which can be advantageous for treating larger areas like the forehead. Some patients notice results faster with Dysport, often within 2-3 days. The units are measured differently from Botox, so you’ll need more Dysport units to achieve the same effect, but the cost per treatment is typically comparable. This spreading quality makes it particularly effective for natural-looking forehead treatments.

Xeomin is often called the “naked” neurotoxin because it doesn’t contain accessory proteins—it’s the purest form of botulinum toxin type A. This may reduce the risk of developing antibodies that could make the treatment less effective over time. For patients who’ve built up resistance to Botox, Xeomin can be an excellent alternative. Results appear within 3-7 days and last 3-4 months, similar to Botox.

Jeuveau is a newer option, FDA-approved in 2019. It’s specifically designed for aesthetic use and is often positioned as a premium alternative to Botox with competitive pricing. Many patients find Jeuveau works just as effectively as Botox with similar onset (3-5 days) and duration (3-4 months). It’s sometimes called “Newtox” in the aesthetic community.

Letybo is one of the most recently FDA-approved neurotoxins available in the United States. It offers the same proven wrinkle-smoothing results as other neurotoxins but often at an exceptional value. Letybo has been used internationally for years with excellent safety and efficacy data. Results appear within 3-7 days and last 3-4 months. For patients seeking quality results at a competitive price point, Letybo is an outstanding option.

Comparing Onset and Duration

While all five neurotoxins provide similar duration of results (3-4 months for most patients), onset times vary slightly:

  • Fastest onset: Dysport (2-3 days)
  • Standard onset: Botox, Jeuveau, Letybo (3-5 days)
  • Slightly slower: Xeomin (3-7 days)

These differences are minimal, and most patients care more about the quality and longevity of results than a day or two difference in onset.

Unit Conversion and Pricing

It’s important to understand that units aren’t equivalent across all neurotoxins:

  • Botox, Xeomin, Jeuveau, and Letybo: Units are generally comparable 1:1
  • Dysport: Approximately 2.5-3 Dysport units = 1 unit of the others

This means if you need 20 units of Botox for your forehead, you might need 50-60 units of Dysport for the same area. However, pricing is adjusted accordingly, so the total cost per treatment is typically similar across brands. At Elan Med Spa, we price all neurotoxins per unit and provide transparent cost estimates during your consultation.

Which One Is Right for You?

The best choice depends on your individual anatomy, treatment goals, and how your body responds. At your consultation at Elan Med Spa, our experienced providers will discuss your aesthetic goals and recommend the option most likely to give you optimal results.

  • First-time patients often start with Botox due to its predictability and extensive track record
  • Faster results or larger areas like the forehead? Dysport might be ideal
  • Minimize protein exposure after long-term use? Xeomin is worth considering
  • Premium aesthetic-focused option? Jeuveau offers excellent results
  • Best value without sacrificing quality? Letybo provides outstanding results at competitive pricing

Medical vs. Aesthetic Indications

While all five neurotoxins smooth wrinkles, only certain ones are FDA-approved for specific medical conditions:

  • Botox: Approved for chronic migraines, excessive sweating (hyperhidrosis), muscle spasms, overactive bladder, and more
  • Dysport: Approved for certain muscle spasticity conditions
  • Xeomin, Jeuveau, Letybo: Primarily approved for aesthetic use

If you’re seeking treatment for migraines or hyperhidrosis, Botox is typically the best choice due to its extensive FDA approvals and potential insurance coverage for medical indications.

Can You Switch Between Neurotoxins?

Absolutely! Many patients try different neurotoxins over time to find their favorite, or switch based on current pricing and availability. There’s no medical reason to stick with one brand forever. Some patients even notice that switching neurotoxins periodically may help maintain effectiveness, particularly if they’ve been using the same product for many years. This is one advantage of choosing a practice like Elan Med Spa that offers all five options.

What to Expect at Elan Med Spa

As a physician-owned practice, we prioritize your safety and natural-looking results. Your treatment takes about 15-20 minutes with minimal discomfort and no downtime. We’ll discuss your facial anatomy, movement patterns, and desired outcome to create a personalized treatment plan. During your consultation, we’ll explain which neurotoxin we recommend for your specific needs and why, along with transparent pricing based on the number of units you’ll need.

The Elan Advantage: Having All Five Options

Most med spas carry only one or two neurotoxin brands. At Elan Med Spa, we stock the five most popular FDA-approved options. This gives us the flexibility to:

  • Match you with the best product for your anatomy and goals
  • Offer competitive pricing across multiple brands
  • Switch products if you develop resistance or prefer different results
  • Take advantage of promotional pricing when available
  • Provide options for both aesthetic and medical needs

Real Patient Experiences

Botox patients appreciate its predictability and reliability—they know what to expect and trust the extensive research behind it.

Dysport patients love the fast results and natural-looking forehead smoothing. The slight spreading creates a soft, even appearance.

Xeomin patients often choose it because they’re concerned about developing resistance to Botox or prefer the pure formulation without accessory proteins.

Jeuveau patients enjoy the premium quality and aesthetic-focused branding. Many find it works identically to Botox for their needs.

Letybo patients are thrilled to find a quality neurotoxin that delivers excellent results at a more accessible price point.

Ready to Smooth Away Those Wrinkles?

Whether you choose Botox, Dysport, Xeomin, Jeuveau, or Letybo, you’ll receive expert care from our physician-led team. We’ll help you understand your options, recommend the best choice for your needs, and deliver natural-looking results you’ll love.

Schedule your consultation today:
📞 (910) 484-3526
📍 6415 Brookstone Ln #103, Fayetteville, NC 28314
🌐 Book Online at elanmedspa.com

Serving Fayetteville, Fort Bragg, Hope Mills, and surrounding North Carolina communities.